VALIDATED RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF CINNARIZINE AND DOMPERIDONE IN BULK AND PHARMACEUTICAL DOSAGE FORM
نویسندگان
چکیده
منابع مشابه
A validated RP-HPLC method for simultaneous estimation of Dexrabeprazole and Domperidone in pharmaceutical dosage form
A validated reverse phase high performance liquid chromatography method has been developed for the simultaneous determination of Dexrabeprazole and Domperidone in combined dosage form. Chromatography was carried out on a C-18 column (4.6 mm × 250 mm, 5 μm) using Acetonitrile: 0.025 M potassium dihydrogen orthophosphate buffer (pH adjusted to 5.1 with triethylamine) in the ratio of 30:70 (v/v) a...
متن کاملA Validated Rp-hplc Method for Simultaneous Estimation of Amlodipine and Lisinopril in Pharmaceutical Dosage Form
A reverse phase high performance liquid chromatography (RP-HPLC) method for the simultaneous estimation of amlodipine and lisinopril in marketed formulation is developed. The determination was carried out on a Phenomenex C18 (250 x 4.6 mm, 5 μm) column using a mobile phase of 0.02 M phosphate buffer solution: methanol (75:25v/v, pH 7.0). The flow rate was 1.0ml/min with detection at 212 nm. The...
متن کاملSimultaneous Estimation of Naproxen Sodium and Domperidone Maleate in Bulk and Pharmaceutical Dosage Form by Modified RP-HPLC Method
A modified RP-HPLC method with UV detection has been developed and validated for the simultaneous estimation of Naproxen sodium (NAP) and Domperidone maleate (DOM) in bulk and pharmaceutical dosage form. Chromatography was carried out on a sunfire C18 column (5 μm, 250 mm x 4.6 mm, i.d.) using a mixture of phosphate buffer (pH 6.5 adjusted with orthophosphoric acid) and acetonitrile in the rati...
متن کاملValidated Rp- Hplc Method for Simultaneous Estimation of Metformin Hydrochloride and Benfotiamine in Bulk Drug and in Pharmaceutical Dosage Form
A new simple, precise, accurate, selective and economical RP-HPLC method has been developed and validated for simultaneous estimation of Metformin Hydrochloride (MET) and Benfotiamine (BEN) in tablet dosage form. The method was carried out on a Waters column C-18 (250 mm x 4.6 mm, 5 μm) with a mobile phase consisting of water (pH 3.2 adjusted with ortho-phosphoric acid) and acetonitrile (75:25 ...
متن کاملSimultaneous RP-HPLC and UV Spectroscopic Method Development and Validation for Estimation of Ibandronate Sodium in Bulk and Pharmaceutical Dosage Form
The present study describes a simple, accurate, precise and cost effective UV-Vis Spectroscopic and RP-HPLC method for the estimation of Ibandronate sodium (IBN). The determination of Ibandronate sodium (IBN) was performed by both UV and RP-HPLC method using 215 nm as the determination wavelength. The drug was dissolved in NaOH solution (0.1N NaOH) for estimation in UV and in distilled water fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmaceutical and Scientific Innovation
سال: 2013
ISSN: 2277-4572
DOI: 10.7897/2277-4572.02218